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Brent Dixon

PhD

Senior Research Scientist (Parasitology), Section Head, Foodborne Viruses, Parasites and Other Disease Agents, Microbiology Research Division, Bureau of Microbial Hazards, Food Directorate, Health Canada

Emplacement

Ottawa, Ontario

Mots clés

Giardia, Cryptosporidium, Cyclospora, Toxoplasma, zoonotic, foodborne

Recherche d'intérêts

My research is focused mainly on the detection, characterization and control of foodborne protozoan parasites including Giardia, Cryptosporidium, Cyclospora, and Toxoplasma. Specifically, I am involved in the development of methods for the elution, concentration, and detection of these pathogens in foods and clinical samples, using microscopy, flow cytometry, and PCR-based molecular methods. I am also very interested in the molecular characterization of species, genotypes and sub-types of these parasites for the purposes of source tracking and studying transmission patterns. I am currently involved in long term surveillance studies on protozoan parasites in food and environmental samples. I am also involved in collaborative studies looking at the survivability and disinfection of protozoan parasites. I am the co-founder and chair of the Food and Environmental Parasitology Network established at Health Canada in 2009.

Publications pertinentes

Amoebae
Anisakiasis
Cryptosporidiosis
Cyclosporiasis
Detection/Diagnostics
Diphyllobothriasis
Fishes
Food
Genomics
Giardiasis
Host-Parasite Interactions
Inactivation/Disinfection
Livestock
Marine Mammals
Northern/Aboriginal Issues
Public Health
Shellfish
Surveillance
Toxoplasmosis
Veterinary

Publications pertinentes

Dixon, B. R.  2023. Protozoa: Cryptosporidium spp.  In Encyclopedia of Food Safety (FOSA), Vol. 2 (2 ed.).  Motarjemi, Y. (ed.). Academic Press, Waltham, MA. Published online early (Oct. 2022): https://www.sciencedirect.com/science/article/pii/B9780128225219000551


Moakhar, Roozbeh Siavash, Rohan Mahimkar, Arash Khorrami Jahromi, Sahar Sadat Mahshid, Carolina del Real Mata, Yao Lu, Brent Dixon, John Gilleard, Alexandre J. da Silva, Momar Ndao, Sara Mahshid. 2023. Aptamer-based electrochemical microfluidic biosensor for the detection of Cryptosporidium parvum. ACS Sensors 8(6): 2149-2158. doi: 10.1021/acssensors.2c01349. 


Merks, Harriet, Ryan Boone, Nicol Janecko, Mythri Viswanathan, Brent R. Dixon. 2023. Foodborne protozoan parasites in fresh mussels and oysters purchased at retail in Canada. International Journal of Food Microbiology 399, 110248, ISSN 0168-1605, https://doi.org/10.1016/j.ijfoodmicro.2023.110248.

 

Yanta, Christine A., John R. Barta, Antoine Corbeil, Hervé Menan, Karine Thivierge, Robert Needle, Muhammad Morshed, Brent R. Dixon, James D. Wasmuth, and Rebecca A. Guy. 2022. Genotyping Canadian Cyclospora cayetanensis isolates to supplement cyclosporiasis outbreak investigations. Microorganisms (Special issue: Genomic Tools for the Surveillance and Investigation of Foodborne Disease and Enteric Zoonoses). 10(2):447. https://doi.org/10.3390/microorganisms10020447

 

Yanta, Christine A., Stephen M. J. Pollo, John R. Barta, Sarah J. Reiling, James D. Wasmuth, Brent R. Dixon, and Rebecca A. Guy. 2022. Draft hybrid genome assembly of a Canadian Cyclospora cayetanensis isolate. Microbiology Resource Announcements 11(2): e01072-21

https://doi.org/10.1128/mra.01072-21

 

Hassan, Eman M., Brent R. Dixon, Syed Sattar, Maria C. DeRosa, Asma Iqbal and Banu Ormeci. 2021. A review of Cryptosporidium spp. and their detection in water. Water Science and Technology 83 (1): 1–25. doi: https://doi.org/10.2166/wst.2020.515.


Dixon, B.R. 2021. Giardia duodenalis in humans and animals – transmission and disease. Special Issue “Foodborne and waterborne zoonotic parasites of veterinary and medical importance”. Res. Vet. Sci. 135: 283-289. ISSN 0034-5288, https://doi.org/10.1016/j.rvsc.2020.09.034.


Reiling, S.J., Merks, H., Zhu, S., Boone, R., Corneau, N., Dixon, B.R. 2021. A cloth-based hybridization array system for rapid detection of the food- and waterborne protozoan parasites Giardia duodenalisCryptosporidium spp. and Toxoplasma gondii. Food Waterborne Parasitol. 2021 Aug 11;24:e00130. doi: 10.1016/j.fawpar.2021.e00130. PMID: 34458600; PMCID: PMC8379661.

 

Hassan, Eman M., Brent R. Dixon, Syed A. Sattar, Andrew Stalker, Banu Örmeci, Maria C. DeRosa. 2021. Highly sensitive magnetic-microparticle-based aptasensor for Cryptosporidium parvum oocyst detection in river water and wastewater: Effect of truncation on aptamer affinity. Talanta 222, 121618,

ISSN 0039-9140, https://doi.org/10.1016/j.talanta.2020.121618.

 

Pollo, Stephen M.J., Sarah J. Reiling, Janneke Wit, Matthew L. Workentine, Rebecca A. Guy, G. William Batoff, Janet Yee, Brent R. Dixon and James D. Wasmuth. 2020. Benchmarking hybrid assemblies of Giardia and prediction of widespread intra-isolate structural variation. Parasites and Vectors 13:108. https://doi.org/10.1186/s13071-020-3968-8. 

 

Hutter, Juliana Ayres, Réjean Dion, Alejandra Irace-Cima, Marc Fiset, Rebecca Guy, Brent Dixon, Jeannie Lisette Aguilar, Julien Trépanier and Karine Thivierge. 2020. Cryptosporidium spp.: human incidence, molecular characterization and associated exposures in Québec, Canada (2016-2017). PLoS ONE 15(2): e0228986. https://doi.org/10.1371/journal.pone.0228986.

 

Shapiro, Karen, Lillian Bahia-Oliveira, Brent Dixon, Aurélien Dumètre, Luz A. de Wit, Elizabeth VanWormer and Isabelle Villena. 2019. Environmental transmission of Toxoplasma gondii: Oocysts in water, soil and food. Food Waterborne Parasitol. 15: https://doi.org/10.1016/j.fawpar.2019.e00049  

Reiling S.J. and Dixon B.R. 2019. Toxoplasma gondii: How an Amazonian parasite became an Inuit health issue. Can. Commun. Dis. Rep. 45(7/8):183–90. https://doi.org/10.14745/ccdr.v45i78a03


Reiling, S.J., L. Measures, S. Feng, R. Boone, H. Merks and B.R. Dixon. 2019. Toxoplasma gondii, Sarcocystis sp., and Neospora caninum-like parasites in seals from northern and eastern Canada: potential risk to consumers. Food Waterborne Parasitol. 17 (2019) e00067.

 

Iqbal, Asma, Juewen Liu, Brent Dixon, Bahram Zargar and Syed Sattar. 2019. Development and application of DNA-aptamer-coupled magnetic beads and aptasensors for the detection of Cryptosporidium parvum oocysts in drinking and recreational water resources. Can. J. Microbiol. 65: 851-857. https://doi.org/10.1139/cjm-2019-0153.

 

Pollo, Stephen M. J., Sarah J. Reiling, Janneke Wit, Matthew L. Workentine, Rebecca A. Guy, G. William Batoff, Janet Yee, Brent R. Dixon, and James D. Wasmuth. 2019. Nanopore sequencing of Giardia reveals widespread intra-isolate structural variation. bioRxiv 323541; doi: https://doi.org/10.1101/343541 (Preprint).

 

Jain, Sona, Zhicheng Huang, Brent Dixon, Syed Sattar, and Juewen Liu. 2019. Cryptosporidium parvum oocyst directed assembly of gold nanoparticles and graphene oxide. Frontiers of Chemical Science and Engineering 13:608-615. https://doi.org/10.1007/s11705-019-1813-4


Maal-Bared, Rasha, Brent Dixon and Diana Axelsson-Olsson. 2019. Fate of internalized Campylobacter jejuni and Mycobacterium avium from encysted and excysted Acanthamoeba polyphaga. Exp. Parasitol. 199: 104-110.

 

Iqbal, A., N. Janecko, F. Pollari, and B. Dixon. 2018. Prevalence and molecular characterization of Toxoplasma gondii DNA in retail fresh meats in Canada. Food Waterborne Parasitol. 13: 1-9. https://doi.org/10.1016/j.fawpar.2018.e00031





Contacter

Banting Research Centre

251 Sir Frederick Banting Driveway, P.L. 2204E

Ottawa, ON K1A 0K9

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