Karine Thivierge

PhD

Head of Parasitology Laboratory, Institut national de santé publique du Québec (INSPQ) - Laboratoire de santé publique du Québec (LSPQ) [Québec Public Health Laboratory]

Location

Ste-Anne-de-Bellevue, Quebec, Canada

Keywords

Intestinal and Blood Parasites, Tick-Borne Diseases, Microsporidia

Research interests

The Parasitology Laboratory is part of the LSPQ, which acts as the provincial reference laboratory in microbiology and quality assurance. The laboratory offers a wide range of analytical services for the detection and identification of enteric parasites and medically important arthropods. As a center of excellence in parasitology, it provides several training programs in the diagnostics of intestinal and blood parasites to healthcare professionals.

In line with the mission of the Parasitology Laboratory, my research interests focus on the development of new molecular-based diagnostic tests for detection of intestinal parasites and on surveillance of emerging vector-borne diseases. Prior to this position, my research activities were centered on the understanding of the biology and biochemistry of helminth parasites (Schistosoma mansoni and Fasciola hepatica), and on the interplay between parasites and their hosts. In terms of this network, I am interested in establishing new collaborations related to the field of public health.

Expertise in

Cryptosporidiosis

Cyclosporiasis

Detection/Diagnostics

Public Health

Surveillance

Ticks

Toxoplasmosis

Relevant publications

Musonera JB, Valiquette L, Baron G, Milord F, Marcoux D, Thivierge K, Bedard-Dallaire S, Pelletier AA, Lachance R, Bourget J, Simard C, Cantin E, Abbasi F, Haraoui LP, Carignan A. Management and clinical outcomes of Lyme disease in acute care facilities in 2 endemic regions of Quebec, Canada: a multicentre retrospective cohort study. CMAJ Open. 2022 Jun 28;10(2):E570-E576. doi: 10.9778/cmajo.20210063.

Yanta CA, Barta JR, Corbeil A, Menan H, Thivierge K, Needle R, Morshed M, Dixon BR, Wasmuth JD, Guy RA. Genotyping Canadian Cyclospora cayetanensis Isolates to Supplement Cyclosporiasis Outbreak Investigations. Microorganisms. 2022 Feb 15;10(2):447. doi: 10.3390/microorganisms10020447.

Ripoche M, Bouchard C, Irace-Cima A, Leighton P, Thivierge K. Current and future distribution of Ixodes scapularis ticks in Québec: Field validation of a predictive model. PLoS One. 2022 Feb 3;17(2):e0263243. doi: 10.1371/journal.pone.0263243.

Forest-Bérard K, Ripoche M, Irace-Cima A, Thivierge K, Adam-Poupart A. More than ticking boxes: Training Lyme disease education ambassadors to meet outreach and surveillance challenges in Québec, Canada.PLoS One. 2021 Oct 12;16(10):e0258466. doi: 10.1371/journal.pone.0258466.

Duplaix L, Wagner V, Gasmi S, Lindsay LR, Dibernardo A, Thivierge K, Fernandez-Prada C, Arsenault J. Exposure to Tick-Borne Pathogens in Cats and Dogs Infested With Ixodes scapularis in Quebec: An 8-Year Surveillance Study. Front Vet Sci. 2021 Jul 15;8:696815. doi: 10.3389/fvets.2021.696815.

Adam-Poupart A, Drapeau LM, Bekal S, Germain G, Irace-Cima A, Sassine MP, Simon A, Soto J, Thivierge K, Tissot F. Occupations at risk of contracting zoonoses of public health significance in Québec. Can Commun Dis Rep. 2021 Jan 29;47(1):47-58. doi: 10.14745/ccdr.v47i01a08.

Mathew R, Wunderlich J, Thivierge K, Cwiklinski K, Dumont C, Tilley L, Rohrbach P, Dalton JP. Biochemical and cellular characterisation of the Plasmodium falciparum M1 alanyl aminopeptidase (PfM1AAP) and M17 leucyl aminopeptidase (PfM17LAP). Sci Rep. 2021 Feb 3;11(1):2854. doi: 10.1038/s41598-021-82499-4.

Guy RA, Yanta CA, Muchaal PK, Rankin MA, Thivierge K, Lau R, Boggild AK. Molecular characterization of Cryptosporidium isolates from humans in Ontario, Canada. Parasit Vectors. 2021 Jan 22;14(1):69. doi: 10.1186/s13071-020-04546-9.

Guillot C, Badcock J, Clow K, Cram J, Dergousoff S, Dibernardo A, Evason M, Fraser E, Galanis E, Gasmi S, German GJ, Howse DT, Jardine C, Jenkins E, Koffi J, Kulkarni M, Lindsay LR, Lumsden G, McKay R, Moore K, Morshed M, Munn D, Nelder M, Nocera J, Ripoche M, Rochon K, Russell C, Slatculescu A, Talbot B, Thivierge K, Voordouw M, Bouchard C, Leighton P. Sentinel surveillance of Lyme disease risk in Canada, 2019: Results from the first year of the Canadian Lyme Sentinel Network (CaLSeN). Can Commun Dis Rep. 2020 Oct 1;46(10):354-361. doi: 10.14745/ccdr.v46i10a08.

Shiels J, Cwiklinski K, Alvarado R, Thivierge K, Cotton S, Gonzales Santana B, To J, Donnelly S, Taggart CC, Weldon S, Dalton JP. Schistosoma mansoni immunomodulatory molecule Sm16/SPO-1/SmSLP is a member of the trematode-specific helminth defence molecules (HDMs). PLoS Negl Trop Dis. 2020 Jul 9;14(7):e0008470.

doi: 10.1371/journal.pntd.0008470.

Gaulin C, Ramsay D, Thivierge K, Tataryn J, Courville A, Martin C, Cunningham P, Désilets J, Morin D, Dion R. Acute Toxoplasmosis among Canadian Deer Hunters Associated with Consumption of Undercooked Deer Meat Hunted in the United States. Emerg Infect Dis. 2020 Feb;26(2):199-205. doi: 10.3201/eid2602.191218.

Ayres Hutter J, Dion R, Irace-Cima A, Fiset M, Guy R, Dixon B, Aguilar JL, Trépanier J, Thivierge K. Cryptosporidium spp.: Human incidence, molecular characterization and associated exposures in Québec, Canada (2016-2017). PLoS One. 2020 Feb 13;15(2):e0228986. doi: 10.1371/journal.pone.0228986.

Contact

20045 Chemin Sainte-Marie

Sainte-Anne-de-Bellevue, QC H9X 3R5

karine.thivierge@inspq.qc.ca